Study increases hope of nerve repair
Nerves damaged by brain or spinal cord injury could be regenerated
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Friday, 07, Nov 2008 12:39
Researchers have discovered it may be possible to regenerate nerves damaged by brain or spinal cord injury.
The study is a break from past theories and used genetic techniques to demonstrate re-growth is primarily regulated from within the cells themselves.
Author of the study Zhigang He revealed: "This is the first time it has been possible to see such significant regeneration by manipulating single molecules.
"We believe that these findings have opened up the possibility for making small-molecule drugs or developing other approaches to promote axon regeneration." He added.
Past studies focussed on removing inhibitory molecules from the neurons' environment and had limited effects.
The key for controlling cell growth in neurons occurs during development but is down regulated when they matured and almost stops when they are damaged, Mr He believes preventing this might cause regeneration.
He and his fellow researchers also think it may be possible to achieve neuron re-growth through pharmacologic means.