Scientists discover skin cancer 'scent'
Thursday, 21 Aug 2008 08:41
Odours from human skin could be used to identify skin cancer
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Scientists have declared that odours from human skin could be used to identify skin cancer.
The findings, to be presented at the 236th meeting of the American Chemical Society, are expected to help in the detection of basal cell carcinoma, the most common type, and other forms of skin cancer.
Researchers sampled air above basal cell tumours and found a different profile of chemical compounds compared to skin located on the same area in healthy subjects.
"Our findings may someday allow doctors to screen for and diagnose skin cancers at very early stages," said author Michelle Gallagher.
Human skin produces numerous airborne chemical molecules known as volatile organic compounds (VOCs) many of which can be detected by their smell.
Scientists compared VOC profiles from basal cell carcinoma sites in 11 patients with those of 11 healthy individuals.
Differences were witnessed in the amounts of specific compounds – including squamous cell carcinoma and melanoma, the most serious form of skin cancer.
While more research is required into the understanding of the chemicals related to skin odour and cancer, scientists are optimistic for its implications in the future.
"Chemical biomarkers may eventually serve as objective clinical markers of disease if effective sensor technology can be developed," said Monell analytical organic chemist George Preti.